My SAS Jimmy has a Detroit with a 70. Once in awhile it would unload or buck. Not enough for me to worry. Like others said, get used to it. Just don't loan your vehicle to a non-wheeler to drive.
I had a welded rear (spool) in my super lightweight Samurai. It actually was pretty decent on the street, just had to turn tight corners kinda slow.
I have had stock Powerlock lockers in two of my Cummins Dodges. One Auto, one Stick. The auto was a SRW and not noticeable. My current one is a Dually and has drag around corners. Nothing serious though.