i have changed 3 v10s. they are a pain in the ass to work on. the intakes need to come off to get them out of the truck. it would be a nightmare to do in a truck. i was lucky enough to do them in a motor home so the dog house could come out and was a major help working on it from the rear as well. the coils are a pain to get to on the back side of the motor. i also think the exhaust had issues as well on them if i remember correctly. we went through 3 motors before we got a good one from a yard. they are big heavy monsters.
im sure nuggets while chime in here if he see's this. he did more research on them then i did. how ever i got good enough to have one in and out in 12 hours from start to finish with bumper reinstalled and all.